What is the standard Wegovy titration schedule?

Per the FDA label, Wegovy (semaglutide) starts at 0.25 mg once weekly for 4 weeks, then steps up every 4 weeks: 0.5 mg, 1 mg, 1.7 mg, and finally the 2.4 mg maintenance dose from week 17. If 2.4 mg is not tolerated, 1.7 mg weekly is an acceptable maintenance dose.

How fast is tirzepatide (Zepbound / Mounjaro) dose increased?

Tirzepatide starts at 2.5 mg once weekly for 4 weeks, then increases to 5 mg. After that, the dose may be raised in 2.5 mg increments (7.5, 10, 12.5, 15 mg) with at least 4 weeks at each step, only if needed. 5, 10 and 15 mg are the recommended maintenance doses; 15 mg weekly is the maximum.

Can you stay on a GLP-1 dose longer than 4 weeks before escalating?

Yes. The FDA labels explicitly allow delaying escalation, and prescribers routinely hold a dose longer than 4 weeks for nausea or other tolerability issues. The 4-week cadence is the default trial protocol, not a requirement — dose changes are always a prescriber decision.

GLP-1 Dose Titration Schedule

Your plan

MedicationSchedules follow the current FDA prescribing information for each brand.

First injection dateSaved in your browser, so your schedule is here when you come back.

Your current label-schedule dose

0.25 mg / week

Label schedule

The labels explicitly allow delaying escalation — prescribers routinely hold a step longer than 4 weeks for nausea or other tolerability issues, and for Ozempic, Zepbound and Mounjaro the steps beyond the first maintenance dose are only taken if needed. This page shows the label's default cadence, not a directive. If you've been held at a dose, shift your start date back until the highlighted step matches what you're actually injecting.

Weeks on treatment—

Maintenance dose begins—

Maintenance dose—

Keep it going

Want reminders and progress tracking? TheGLP-1 Progress Trackersaves your schedule alongside your weekly weigh-ins.

How this works

Methodology reviewed July 2026

This tool reproduces the default step-up cadence from the current FDA prescribing information for semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) and maps it onto your own calendar from your first injection date. Each label uses a fixed 4-week interval per step, so the tool advances one step every 28 days and highlights the dose you'd be on today, when the next step-up lands, and when the maintenance dose begins. It is a calendar view of the label's default schedule — not medical advice and not a directive to escalate.

Formula

Current step index = floor(days since first injection / 28), capped at the last labeled step
Step start date    = first injection date + (step index × 28 days)
Wegovy (semaglutide):      0.25 → 0.5 → 1 → 1.7 → 2.4 mg/week (maintenance 2.4, or 1.7 if not tolerated)
Ozempic (semaglutide):     0.25 → 0.5 → 1 → 2 mg/week (steps beyond 0.5 only if more glycemic control needed)
Zepbound (tirzepatide):    2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg/week (5/10/15 are maintenance options)
Mounjaro (tirzepatide):    2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg/week (steps beyond 5 only if needed)

Inputs

Medication/brand · First injection date

Outputs

Current label-schedule dose · Next step-up dose and date · Full escalation timeline · Maintenance dose and start date

Assumptions

Each step is held for exactly 4 weeks, the default label interval.
You started at the label's starter dose on your entered first-injection date.
The schedule follows the current FDA prescribing information for the selected brand.

Limitations

The labels explicitly allow delaying escalation; prescribers routinely hold a dose longer than 4 weeks for tolerability.
Steps beyond the first maintenance option (Ozempic, Zepbound, Mounjaro) are only taken if additional glycemic control or weight loss is needed.
If you've been held at a dose, the highlighted step won't match your real injection — shift your start date back to realign.

Safety

Never escalate or stretch a dose on your own — dose changes are always a prescriber decision that overrides anything shown here.
If 2.4 mg semaglutide is not tolerated, 1.7 mg weekly is an acceptable maintenance dose per the Wegovy label.

References

This calculator is for educational purposes only and is not medical advice, diagnosis, or treatment. Results are estimates based on published formulas and population averages — your individual values may differ. Nothing here is calculated on a server: everything runs in your browser and no data is stored or sent anywhere. Always consult a qualified clinician before making health, medication, or training decisions.