| Tirzepatide for the Treatment of Cannabis Use DisorderNCT07265752 · Brigham and Women's Hospital | Tirzepatide | Phase 2 | Not yet recruiting●Now tracking | 6 | 2027-03-01 |
| Effects of Tirzepatide on Gut Microbiota and Gastrointestinal Function After Drug Withdrawal in Obese PatientsNCT07847515 · Nanjing First Hospital, Nanjing Medical University | Tirzepatide | — | Not yet recruiting●Now tracking | 80 | 2027-02-01 |
| Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant AccessNCT07858331 · Kristin Clemens | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 880 | 2027-01-01 |
| GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF RegistryNCT07787936 · Miedziowe Centrum Zdrowia SA | LiraglutideDulaglutide | — | Not yet recruiting●Now tracking | 150 | 2027-01-01 |
| Impact of BPC-157 on Recovery Following Rotator Cuff Repair SurgeryNCT07803250 · University of Arkansas | BPC-157 | Phase 1 | Not yet recruiting●Now tracking | 30 | 2027-01-01 |
| Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial CancerNCT07078838 · UNC Lineberger Comprehensive Cancer Center | Tirzepatide | Phase 2 | Not yet recruiting●Now tracking | 40 | 2027-01 |
| A Study of Orforglipron (LY3502970) in Chinese Participants With Obesity or Overweight and Weight-Related Health ProblemsNCT07790861 · Eli Lilly and Company | Orforglipron | Phase 3 | Not yet recruiting●Now tracking | 192 | 2026-12 |
| SYNCHRONIZE®-START- A Study to Test Whether Survodutide Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose WeightNCT07855900 · Boehringer Ingelheim | SemaglutideTirzepatide | Phase 3 | Not yet recruiting●Now tracking | 350 | 2026-11-07 |
| Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 DiabetesNCT07866066 · Amgen | Semaglutide | Phase 3 | Not yet recruiting●Now tracking | 1300 | 2026-11-02 |
| Comparing Different Medication Regimens to Maintaining Weight Loss Among Adults With Obesity Using GLP-1sNCT07832084 · Jing Luo | SemaglutideTirzepatide | Phase 4 | Not yet recruiting●Now tracking | 60 | 2026-11-01 |
| Metabolic Surgery for Atrial Fibrillation EliminationNCT07027969 · Ali Aminian | LiraglutideDulaglutide | Phase 4 | Not yet recruiting | 100 | 2026-11-01 |
| Switching to Oral Weight Management Pharmacotherapy to Prevent Weight Regain After GLP-1 Therapy DiscontinuationNCT07729332 · Massachusetts General Hospital | Orforglipron | Phase 4 | Not yet recruiting●Now tracking | 60 | 2026-11-01 |
| Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)NCT07099742 · Dr. Md. Alimur Reza | Tirzepatide | — | Not yet recruiting●Now tracking | 364 | 2026-11 |
| GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way ForwardNCT06977438 · University of Minnesota | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 1020 | 2026-10-15 |
| A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide MedicationNCT07868354 · Novo Nordisk A/S | Tirzepatide | Phase 1 | Not yet recruiting●Now tracking | 60 | 2026-10-08 |
| FutureShape FamilyNCT07872904 · Signe Torekov | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 400 | 2026-10-01 |
| Danish Trial of Weight Loss to Reduce Atrial Fibrillation ProgressionNCT07816744 · Axel Brandes | Semaglutide | — | Not yet recruiting●Now tracking | 480 | 2026-10-01 |
| A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or ObesityNCT07845500 · Pfizer | Tirzepatide | Phase 3 | Not yet recruiting●Now tracking | 660 | 2026-10-01 |
| Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea: A Randomised Comparative Effectiveness TrialNCT07846865 · Woolcock Institute of Medical Research | Tirzepatide | Phase 2/Phase 3 | Not yet recruiting●Now tracking | 256 | 2026-10-01 |
| Randomized Controlled Trial of Tirzepatide for Methamphetamine Use DisorderNCT07825857 · University of Texas Southwestern Medical Center | Tirzepatide | Phase 2 | Not yet recruiting●Now tracking | 228 | 2026-10-01 |
| Comparison of [68Ga]Ga-HBED-CC-PEG6-Exendin-4 and [68Ga]Ga-HBED-CC-Exendin-4 PET/CT for Insulinoma LocalizationNCT07808879 · Peking Union Medical College Hospital | Exenatide | — | Recruiting●Now tracking | 20 | 2026-10-01 |
| PATHS-T2D: A Recall-by-Genotype Study of Physiologic and Pharmacologic ResponsesNCT07739537 · Massachusetts General Hospital | Orforglipron | Phase 4 | Not yet recruiting●Now tracking | 100 | 2026-10-01 |
| Semaglutide 2.4 mg Once Weekly for Recurrent Weight Gain After Metabolic and Bariatric Surgery (RESURGE)NCT07859150 · General Committee of Teaching Hospitals and Institutes, Egypt | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 104 | 2026-10 |
| Immediate Versus Criterion-triggered Semaglutide for Suboptimal Clinical Response One Year After Primary Metabolic and Bariatric SurgeryNCT07859189 · General Committee of Teaching Hospitals and Institutes, Egypt | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 100 | 2026-10 |
| Tapered Versus Abrupt Discontinuation of Semaglutide After Treatment of Recurrent Weight Gain or Suboptimal Response Following Metabolic and Bariatric SurgeryNCT07859176 · General Committee of Teaching Hospitals and Institutes, Egypt | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 100 | 2026-10 |
| Semaglutide Before Primary Metabolic and Bariatric Surgery in Patients With BMI 60 kg/m² or HigherNCT07859137 · General Committee of Teaching Hospitals and Institutes, Egypt | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 100 | 2026-10 |
| Semaglutide Given Before and After Conversion of Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Recurrent Weight GainNCT07859163 · General Committee of Teaching Hospitals and Institutes, Egypt | Semaglutide | Phase 4 | Not yet recruiting●Now tracking | 100 | 2026-10 |
| Phase II Study of Switching From Dulaglutide to PG-102(MG12) in Type 2 Diabetes MellitusNCT07677891 · ProGen. Co., Ltd. | Dulaglutide | Phase 2 | Not yet recruiting | 60 | 2026-10 |
| A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide MedicationNCT07855133 · Novo Nordisk A/S | Semaglutide | Phase 1 | Not yet recruiting●Now tracking | 60 | 2026-09-30 |
| Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)NCT07817875 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting●Status change | 150 | 2026-09-25 |
| NAION in Non-Diabetic Obese Patients Using GLP-1 Receptor Agonists: A Real-World StudyNCT07846956 · Istanbul Saglik Bilimleri University | Tirzepatide | — | Not yet recruiting●Now tracking | 28 | 2026-09-21 |
| Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized TrialNCT07734792 · yifang zhu | Tirzepatide | Phase 2/Phase 3 | Not yet recruiting●Now tracking | 726 | 2026-09-20 |
| A Study of BGM0504 in Early T2DM With ObesityNCT07743983 · BrightGene Bio-Medical Technology Co., Ltd. | Semaglutide | Phase 3 | Recruiting●Now tracking | 372 | 2026-09-17 |
| Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the EndometriumNCT06073184 · GynOncTrials | Semaglutide | Phase 2 | Recruiting●Now tracking | 71 | 2026-09-17 |
| Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to CagrisemaNCT07817251 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Recruiting●Status change | 210 | 2026-09-16 |
| Tirzepatide for Treatment of CCCANCT07734870 · Johns Hopkins University | Tirzepatide | Phase 2 | Recruiting●Now tracking | 20 | 2026-09-15 |
| A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or ObesityNCT07803744 · Eli Lilly and Company | Tirzepatide | Phase 1 | Recruiting●Status change | 18 | 2026-09-11 |
| IBI3042 Study in Healthy Participants and Overweight or Obese ParticipantsNCT07793019 · Innovent Biologics (Suzhou) Co. Ltd. | Orforglipron | Phase 1 | Recruiting●Status change | 104 | 2026-09-07 |
| A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 DiabetesNCT07668336 · Eli Lilly and Company | DulaglutideOrforglipron | Phase 3 | Not yet recruiting | 170 | 2026-09 |
| MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal DiseaseNCT07478653 · Oelisoa Andriankaja | Semaglutide | — | Recruiting●Now tracking | 50 | 2026-08-31 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC35 Injection in Participants With Obesity or OverweightNCT07842640 · Ascletis Pharma (China) Co., Limited | Tirzepatide | Phase 1 | Recruiting●Now tracking | 84 | 2026-08-27 |
| A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesNCT07357740 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Withdrawn | 0 | 2026-08-27 |
| A Neuropsychobiological Approach to Optimize Patient Selection for GLP-1-based Pharmacotherapy for Weight Management Across the Binge Eating SpectrumNCT07870538 · Universitaire Ziekenhuizen KU Leuven | Semaglutide | Phase 4 | Recruiting●Now tracking | 96 | 2026-08-26 |
| A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 ObesityNCT07794579 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting●Status change | 2001 | 2026-08-26 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 DiabetesNCT07282613 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Recruiting●Status change | 80 | 2026-08-04 |
| A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightNCT07745504 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Recruiting●Status change | 285 | 2026-08-04 |
| Imaging in Semaglutide StudyNCT07695454 · The Cleveland Clinic | Semaglutide | — | Recruiting●Now tracking | 10 | 2026-07-30 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan FastingNCT07613307 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting●Status change | 130 | 2026-07-15 |
| Body Composition Changes After Initiation of GLP-1 Receptor Agonists in Adults With Obesity or Type 2 DiabetesNCT07835360 · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | Tirzepatide | — | Recruiting●Now tracking | 200 | 2026-07-10 |
| Trial of Innovative Fat-loss Focused Approaches in Patients With Class I Obesity: a Comparative StudyNCT07866183 · National Medical Research Center for Therapy and Preventive Medicine | Tirzepatide | — | Recruiting●Now tracking | 120 | 2026-06-29 |
| A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesNCT07668388 · Novo Nordisk A/S | Semaglutide | Phase 2 | Recruiting●Now tracking | 300 | 2026-06-22 |
| A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightNCT07357766 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Withdrawn | 0 | 2026-06-22 |
| Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor AgonistsNCT07702461 · Ohio State University | LiraglutideDulaglutideExenatide | — | Recruiting●Now tracking | 300 | 2026-06-12 |
| TP04HN106 in the Treatment of Patients With Amyotrophic Lateral SclerosisNCT06726577 · Talengen Institute of Life Sciences, Shenzhen, P.R. China. | Liraglutide | Phase 1/Phase 2 | Recruiting | 60 | 2026-06-04 |
| GLP-1 Receptor Agonist Use and Sarcopenia in Obese Individuals Without DiabetesNCT07858864 · Istanbul Saglik Bilimleri University | SemaglutideTirzepatide | — | Recruiting●Now tracking | 42 | 2026-05-30 |
| Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsNCT07607587 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 114 | 2026-05-29 |
| A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLDNCT07527910 · Regeneron Pharmaceuticals | Tirzepatide | Phase 2 | Recruiting●Now tracking | 204 | 2026-05-22 |
| A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Recruiting | 2500 | 2026-05-21 |
| Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)NCT07559500 · National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Tirzepatide | Phase 1 | Recruiting●Now tracking | 176 | 2026-05-20 |
| A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightNCT07605052 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed●Status change | 50 | 2026-05-20 |
| Phase 3 Study of LUM-201 in Children With Growth Hormone DeficiencyNCT06948214 · Lumos Pharma | MK-677 | Phase 3 | Recruiting | 150 | 2026-05-20 |
| A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityNCT07597018 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 234 | 2026-05-18 |
| Recombinant Human Thymosin Beta 4 for Injection(NL005) for Acute Myocardial InfarctionNCT07586865 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 2 | Not yet recruiting | 189 | 2026-05-18 |
| RWS of of Liraglutide Alone and in Combination With Orlistat for Weight Loss in Overweight/Obese Patients.NCT07301437 · The Fourth Affiliated Hospital of Zhejiang University School of Medicine | Liraglutide | Phase 4 | Not yet recruiting | 120 | 2026-05-01 |
| Efficacy and Safety of Triple Therapy With Dulaglutide, SGLT2 Inhibitors, and Finerenone in Chinese Adults With Type 2 Diabetes and Chronic Kidney DiseaseNCT07537088 · First Affiliated Hospital of Wannan Medical College | Dulaglutide | Phase 4 | Not yet recruiting | 468 | 2026-05 |
| A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityNCT07557953 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 120 | 2026-04-30 |
| Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple SclerosisNCT07497399 · Johns Hopkins University | Exenatide | Phase 2 | Recruiting | 120 | 2026-04-28 |
| Tirzepatide in Obesity-Driven Endometrial CancerNCT07065552 · UNC Lineberger Comprehensive Cancer Center | Tirzepatide | EARLY_Phase 1 | Recruiting●Now tracking | 20 | 2026-04-27 |
| Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)NCT07527195 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 100 | 2026-04-10 |
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)NCT07547878 · Baylor Research Institute | Semaglutide | Phase 4 | Enrolling by invitation●Now tracking | 64 | 2026-04-08 |
| The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityNCT07218445 · Mayo Clinic | Tirzepatide | Phase 4 | Recruiting●Now tracking | 40 | 2026-04-08 |
| A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial NeoplasiaNCT07107334 · University of Florida | LiraglutideOrforglipron | Phase 2 | Recruiting | 20 | 2026-04-07 |
| A Study to Evaluate ALN-2232 in Participants With ObesityNCT07463846 · Alnylam Pharmaceuticals | Tirzepatide | Phase 1/Phase 2 | Recruiting●Now tracking | 156 | 2026-03-02 |
| Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal TransplantationNCT07678073 · University of Gaziantep | MOTS-c | — | Recruiting | 68 | 2026-03-01 |
| Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKDNCT07187830 · University of Alberta | Semaglutide | — | Recruiting●Now tracking | 52 | 2026-02-23 |
| Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic OutcomesNCT07424430 · LMC Diabetes & Endocrinology Ltd. | Semaglutide | — | Completed●Now tracking | 3392 | 2026-02-20 |
| Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are OverweightNCT07467447 · Hudson Biotech | Retatrutide | Phase 2 | Recruiting | 300 | 2026-02-15 |
| The Evira Study: Additional Support During Obesity TreatmentNCT06836284 · Karolinska Institutet | Liraglutide | — | Recruiting | 40 | 2026-02-13 |
| A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or ObeseNCT07411560 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 100 | 2026-02-09 |
| TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVDNCT07487363 · Hudson Biotech | TB-500Thymosin Beta-4 | Phase 1/Phase 2 | Recruiting | 80 | 2026-02-05 |
| Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.NCT07417631 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 300000 | 2026-02-03 |
| BPC 157 for Acute Hamstring Muscle Strain RepairNCT07437547 · Hudson Biotech | BPC-157 | Phase 2 | Recruiting | 120 | 2026-02-02 |
| Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study)NCT07481734 · Hudson Biotech | Tesamorelin | Phase 2 | Recruiting | 120 | 2026-02-02 |
| MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/ObesityNCT07505745 · Hudson Biotech | MOTS-c | Phase 2 | Recruiting | 120 | 2026-02-02 |
| INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)NCT07417618 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 60000 | 2026-01-27 |
| A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or OverweightNCT07357415 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 600 | 2026-01-24 |
| Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular RiskNCT07619495 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 120000 | 2026-01-20 |
| A Single-Center, Open-Label, Single Ascending Dose Study of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects With Type 2 Diabetes MellitusNCT07347080 · The First Affiliated Hospital of Henan University of Science and Technology | Exenatide | EARLY_Phase 1 | Recruiting | 9 | 2026-01-20 |
| A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightNCT07253285 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Recruiting | 460 | 2026-01-08 |
| Estimating the Impact of Obesity Medications on Clinical and Economic OutcomesNCT07640139 · Indiana University | Liraglutide | — | Enrolling by invitation | 125000 | 2026-01-01 |
| Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have DiabetesNCT07284979 · Kailera | Semaglutide | Phase 3 | Active not recruiting●Now tracking | 1270 | 2025-12-30 |
| A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes MellitusNCT07313813 · Eli Lilly and Company | Dulaglutide | Phase 1 | Completed●Status change | 20 | 2025-12-29 |
| Role of GLP1 RA Dulaglutide on Severe Intracranial AtherosclerosisNCT07282041 · National University of Singapore | Dulaglutide | Phase 2/Phase 3 | Recruiting | 130 | 2025-12-17 |
| Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric RetentionNCT07276763 · Fudan University | Dulaglutide | — | Not yet recruiting | 16509 | 2025-12-10 |
| A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)NCT07241390 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 7140 | 2025-12-01 |
| ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy AgingNCT07871799 · Sheba Medical Center | Semaglutide | Phase 2 | Completed●Now tracking | 31 | 2025-11-17 |
| A Study of Retatrutide (LY3437943) in Participants With Obesity or OverweightNCT07232719 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 250 | 2025-11-17 |
| Weekly GLP-1 Receptor Agonists in Obese Individuals Without DiabetesNCT07834398 · Zagazig University | Dulaglutide | Phase 3 | Completed●Now tracking | 150 | 2025-11-14 |
| Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)NCT07225816 · Novo Nordisk A/S | Liraglutide | Phase 1 | Recruiting | 71 | 2025-11-07 |
| Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideNCT07220759 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 330 | 2025-11-05 |
| Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideNCT07220642 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 300 | 2025-11-05 |
| Efficacy and Safety of Orforglipron in Participants With Peripheral Artery DiseaseNCT07223593 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 1205 | 2025-10-31 |
| Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical TrialNCT07820111 · Zagazig University | Dulaglutide | Phase 3 | Completed●Now tracking | 159 | 2025-10-18 |
| A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)NCT07165028 · Eli Lilly and Company | TirzepatideRetatrutide | Phase 3 | Recruiting | 4500 | 2025-10-15 |
| A Phase 3 Study of HS-20094 in Patients With T2DMNCT07156539 · Jiangsu Hansoh Pharmaceutical Co., Ltd. | Dulaglutide | Phase 3 | Not yet recruiting | 546 | 2025-09-30 |
| A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or OverweightNCT07202884 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 1000 | 2025-09-30 |
| A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietNCT07184086 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Active not recruiting●Now tracking | 80 | 2025-09-26 |
| Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)NCT07188545 · Ohio State University | DulaglutideExenatide | — | Active not recruiting | 23280000 | 2025-09-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the KneeNCT07153471 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting●Status change | 800 | 2025-09-15 |
| A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and RecoveryNCT07752381 · Parlay Wellness | BPC-157 | — | Completed●Now tracking | 40 | 2025-09-01 |
| Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes MellitusNCT07319286 · Ain Shams University | Dulaglutide | Phase 1/Phase 2 | Enrolling by invitation | 50 | 2025-08-04 |
| Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist TherapyNCT06903923 · University of Virginia | Liraglutide | Phase 2 | Recruiting | 120 | 2025-07-31 |
| Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIVNCT06554717 · Massachusetts General Hospital | SermorelinTesamorelin | Phase 2 | Recruiting | 100 | 2025-07-10 |
| Probiotics in Obese Patients Treated With SemaglutideNCT07847593 · Nordic Biotic Sp. z o.o. | Semaglutide | — | Completed●Now tracking | 102 | 2025-07-09 |
| GLP-1s to Enhance Lasting Optimal WeightNCT06861439 · Wake Forest University Health Sciences | Tirzepatide | Phase 4 | Active not recruiting●Now tracking | 40 | 2025-07-07 |
| A Study of BGM0504 in Participants With Type 2 Diabetes in IndonesiaNCT07064486 · BrightGene Bio-Medical Technology Co., Ltd. | Semaglutide | Phase 3 | Active not recruiting●Now tracking | 152 | 2025-07-04 |
| Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility StudyNCT06759701 · M.D. Anderson Cancer Center | Tirzepatide | EARLY_Phase 1 | Recruiting●Now tracking | 30 | 2025-07-02 |
| Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b StudyNCT06937086 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting | 350 | 2025-06-26 |
| Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or OverweightNCT06937099 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting | 290 | 2025-06-26 |
| A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and OsteoarthritisNCT07225829 · 4Moving Biotech | Liraglutide | Phase 2 | Active not recruiting●Status change | 129 | 2025-06-17 |
| The Role of the Amylin Analogue Cagrilintide in Bone MetabolismNCT07010432 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting●Now tracking | 144 | 2025-06-12 |
| A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to HypoglycemiaNCT06982846 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 80 | 2025-06-06 |
| A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termNCT07011667 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 609 | 2025-06-03 |
| Semaglutide for Helping Opioid RecoveryNCT06639464 · Brigham and Women's Hospital | Semaglutide | Phase 2 | Recruiting●Now tracking | 46 | 2025-06-02 |
| A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes MellitusNCT06982859 · Eli Lilly and Company | SemaglutideRetatrutide | Phase 1 | Active not recruiting●Status change | 95 | 2025-06-02 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back PainNCT07035093 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting●Status change | 586 | 2025-05-29 |
| Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.NCT06851962 · Fundación para la Investigación del Hospital Clínico de Valencia | Dulaglutide | Phase 4 | Completed●Status change | 92 | 2025-05-26 |
| Tirzepatide vs Liraglutide in BoneNCT07094568 · National and Kapodistrian University of Athens | Liraglutide | — | Recruiting | 72 | 2025-05-23 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 DiabetesNCT06993792 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 1400 | 2025-05-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related ComorbidityNCT06972459 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 800 | 2025-05-15 |
| A Study of HDM1005 in Participants With T2DM Not Controlled With Diet/Exercise or MetforminNCT07109700 · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Dulaglutide | Phase 2 | Recruiting | 216 | 2025-04-30 |
| A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1NCT06948435 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 487 | 2025-04-30 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)NCT06948422 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 974 | 2025-04-30 |
| A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2NCT06952530 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 487 | 2025-04-30 |
| Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 DiabetesNCT06706284 · Marzieh Salehi | Semaglutide | Phase 4 | Recruiting●Now tracking | 50 | 2025-04-11 |
| A Study of BGM0504 in Participants With ObesityNCT06911203 · BrightGene Bio-Medical Technology Co., Ltd. | Tirzepatide | Phase 2 | Completed●Now tracking | 96 | 2025-04-09 |
| A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideNCT06897475 · Eli Lilly and Company | SemaglutideTirzepatide | Phase 2 | Recruiting●Now tracking | 200 | 2025-03-28 |
| Response to Semaglutide in Non-diabetic Obese Patients With Varying Degrees of Insulin ResistanceNCT06856291 · ETH Zurich | Semaglutide | — | Completed●Now tracking | 40 | 2025-03-15 |
| A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With ObesityNCT06859268 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 643 | 2025-03-05 |
| Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)NCT06854614 · The Cleveland Clinic | Tirzepatide | Phase 4 | Active not recruiting●Now tracking | 150 | 2025-03-01 |
| A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityNCT06780449 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 400 | 2025-02-10 |
| Tirzepatide for Obesity and Meth Use DisorderNCT06745128 · University of Texas Southwestern Medical Center | Tirzepatide | Phase 2 | Completed●Now tracking | 35 | 2025-02-03 |
| To Investigate the Effect of Retatrutide (LY3437943) on Metoprolol Pharmacokinetics in Healthy ParticipantsNCT06808802 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 30 | 2025-02-03 |
| Study of Patients Being Treated With Anti-obesity MedicationNCT06790160 · Texas Tech University | SemaglutideTirzepatide | — | Active not recruiting●Now tracking | 100 | 2025-01-31 |
| A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral NeuropathyNCT06797869 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Completed●Status change | 142 | 2025-01-29 |
| A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)NCT06739122 · Eli Lilly and Company | Dulaglutide | Phase 3 | Recruiting | 55 | 2025-01-10 |
| Semaglutide in Women With Polycystic Ovary Syndrome and ObesityNCT06896981 · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Semaglutide | Phase 2/Phase 3 | Completed●Now tracking | 31 | 2025-01-01 |
| Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor AgonistsNCT07325435 · MaryAnn Banerji | LiraglutideDulaglutide | Phase 4 | Active not recruiting | 60 | 2024-12-21 |
| Assessment of Safety, Tolerability and Drug Levels of Exenatide ImplantNCT05670379 · Vivani Medical, Inc | Exenatide | Phase 1 | Completed | 24 | 2024-12-20 |
| A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes MellitusNCT06700538 · Arrowhead Pharmaceuticals | Tirzepatide | Phase 1/Phase 2 | Recruiting●Now tracking | 180 | 2024-12-04 |
| A Study on How NNC0174-1213 Works in People With Overweight or Obesity.NCT06719011 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed●Now tracking | 178 | 2024-12-03 |
| A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or ObesityNCT06716307 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed●Now tracking | 18 | 2024-12-02 |
| Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent ThalassemiaNCT07370922 · Ain Shams University | Dulaglutide | Phase 2 | Completed | 80 | 2024-11-22 |
| Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA)NCT06191848 · University of Melbourne | Tirzepatide | Phase 4 | Active not recruiting●Now tracking | 352 | 2024-11-19 |
| A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)NCT06672549 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 125 | 2024-11-18 |
| A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related ComorbiditiesNCT06672939 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 150 | 2024-11-18 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothNCT06534411 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed●Status change | 1023 | 2024-11-05 |
| A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have ObesityNCT06662383 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 800 | 2024-11-01 |
| Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesNCT06779929 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 70000 | 2024-11-01 |
| A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or OverweightNCT06649045 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed●Now tracking | 712 | 2024-10-22 |
| Food (Poly)Phenol Metabotypes and Beta-cell Mass and Function.NCT06888167 · Azienda Ospedaliero-Universitaria di Parma | Exenatide | — | Recruiting | 40 | 2024-10-14 |
| Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective SurgeryNCT06500143 · Ciusss de L'Est de l'Île de Montréal | Dulaglutide | — | Completed | 94 | 2024-10-09 |
| Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular RiskNCT07096063 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 887132 | 2024-10-01 |
| Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims DataNCT07088718 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 44671 | 2024-10-01 |
| A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering DrugsNCT05663515 · AstraZeneca | Exenatide | — | Recruiting | 24000 | 2024-09-30 |
| A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 DiabetesNCT06603571 · Eli Lilly and Company | Tirzepatide | Phase 2 | Completed●Now tracking | 367 | 2024-09-20 |
| A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)NCT06584916 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 376 | 2024-09-13 |
| The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic EffectNCT06058585 · The George Institute | Semaglutide | Phase 3 | Recruiting●Now tracking | 2000 | 2024-09-04 |
| Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in BangladeshNCT06449235 · Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders | Exenatide | Phase 4 | Unknown●Status change | 938 | 2024-09 |
| Effect of Liraglutide in Obese Women With Polycystic Ovary SyndromeNCT05965908 · Beni-Suef University | Liraglutide | Phase 3 | Completed | 183 | 2024-08-01 |
| Exenatide For Reducing the Reinforcing Effects of CocaineNCT06252623 · Christopher D. Verrico | Exenatide | Phase 1 | Withdrawn | 0 | 2024-08-01 |
| Holding vs. Continuing Incretin-based Therapies Before Upper EndoscopyNCT06533527 · The Cleveland Clinic | Dulaglutide | Phase 4 | Completed | 69 | 2024-07-31 |
| A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With MetforminNCT06257966 · Beijing Dongfang Biotech Co., Ltd. | DulaglutideExenatide | Phase 3 | Active not recruiting | 600 | 2024-07-17 |
| Fibrosis Lessens After Metabolic SurgeryNCT06374875 · The Cleveland Clinic | Liraglutide | Phase 4 | Recruiting●Now tracking | 120 | 2024-07-11 |
| A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM PatientsNCT06254014 · Beijing Dongfang Biotech Co., Ltd. | Exenatide | Phase 3 | Active not recruiting | 270 | 2024-07-10 |
| Risk Factors Affect Weight Loss Outcomes After Treatment.NCT06482411 · E-DA Hospital | Liraglutide | — | Completed | 3602 | 2024-06-27 |
| A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose WeightNCT06388187 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 300 | 2024-06-24 |
| A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or OverweightNCT06440980 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed●Now tracking | 533 | 2024-06-24 |
| The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical TrialNCT06050577 · Odense University Hospital | Semaglutide | Phase 2 | Active not recruiting●Now tracking | 64 | 2024-06-07 |
| A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)NCT06439277 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting | 300 | 2024-06-03 |
| Diabetes Islet Preservation Immune TreatmentNCT02586831 · Camillo Ricordi and Jay Skyler | Exenatide | Phase 1/Phase 2 | Withdrawn | 0 | 2024-06-01 |
| Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver DiseaseNCT06409130 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Completed | 270 | 2024-05-20 |
| Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesNCT06403761 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 158 | 2024-05-06 |
| A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy ParticipantsNCT06370728 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed●Now tracking | 30 | 2024-05-06 |
| The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)NCT06383390 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 10000 | 2024-04-30 |
| Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)NCT06354660 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed | 537 | 2024-04-10 |
| Study to Evaluate the Safety and Effectiveness of Saxenda® for Weight Management in Routine Clinical Practice in Taiwan.NCT06283641 · Novo Nordisk A/S | Liraglutide | — | Completed | 300 | 2024-04-08 |
| A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes MellitusNCT06235086 · CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Dulaglutide | Phase 3 | Completed | 632 | 2024-04-08 |
| A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and PlaceboNCT06131372 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Completed | 626 | 2024-04-01 |
| Use of Liraglutide in Children Aged 6 to 12 Years With Severe ObesityNCT07590219 · University of Sao Paulo General Hospital | Liraglutide | Phase 4 | Active not recruiting | 30 | 2024-03-30 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminNCT06323161 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 274 | 2024-03-26 |
| A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943NCT06313528 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 85 | 2024-03-20 |
| GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac SurgeryNCT06324461 · The University of Hong Kong | Dulaglutide | Phase 4 | Recruiting | 372 | 2024-03-20 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and ExerciseNCT06323174 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 189 | 2024-03-19 |
| Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)NCT06297603 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 320 | 2024-03-15 |
| A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightNCT06289504 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 34 | 2024-02-27 |
| A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightNCT06207877 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 62 | 2024-02-23 |
| Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)NCT06260722 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 1250 | 2024-02-21 |
| A Study of How CagriSema Works on Appetite in People With Excess Body WeightNCT06267092 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 164 | 2024-02-15 |
| A Study of HS-20094 in Patients With T2DMNCT06901648 · Jiangsu Hansoh Pharmaceutical Co., Ltd. | Dulaglutide | Phase 2 | Completed | 275 | 2024-02-06 |
| Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory IssuesNCT06171152 · University of Chicago | Liraglutide | EARLY_Phase 1 | Suspended | 30 | 2024-01-26 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06221969 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 1024 | 2024-01-16 |
| Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DMNCT06256419 · The Affiliated Hospital of Xuzhou Medical University | Exenatide | — | Recruiting | 300 | 2024-01-01 |
| Pharmacological Treatment - An Overview of Its Role in Managing Childhood ObesityNCT07304141 · Göteborg University | Liraglutide | — | Completed | 128 | 2023-12-20 |
| A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightNCT06131437 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 809 | 2023-11-27 |
| A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightNCT06143956 · Eli Lilly and Company | Tirzepatide | Phase 2 | Recruiting●Now tracking | 1481 | 2023-11-17 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 InhibitorNCT06109311 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed●Now tracking | 546 | 2023-11-10 |
| Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese SubjectsNCT06247748 · Beijing Dongfang Biotech Co., Ltd. | Exenatide | Phase 1 | Completed | 28 | 2023-10-19 |
| A Phase I Study of LY3502970 in Healthy ParticipantsNCT06085482 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 10 | 2023-10-19 |
| Therapeutic Strategies for Microvascular Dysfunction in Type 1 DiabetesNCT05478707 · AdventHealth Translational Research Institute | Dulaglutide | Phase 2 | Recruiting●Status change | 47 | 2023-10-05 |
| A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 DiabetesNCT06010004 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 401 | 2023-09-28 |
| A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06065540 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 2734 | 2023-09-27 |
| A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With MetforminNCT06045221 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed●Now tracking | 1698 | 2023-09-22 |
| A Study of LY3502970 in Chinese Participants With Obesity or Are Overweight With Weight-related ComorbiditiesNCT06023095 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed●Now tracking | 24 | 2023-09-21 |
| Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKDNCT07309094 · Cardenal Herrera University | DulaglutideExenatide | — | Recruiting | 250 | 2023-09-15 |
| A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or ObeseNCT06039826 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 46 | 2023-09-12 |
| Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic SurgeryNCT07374445 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Liraglutide | Phase 4 | Completed | 100 | 2023-09-01 |
| A Research Study Looking at Similarity Between LY3437943 Versions for Different Injection DevicesNCT06003465 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 57 | 2023-08-29 |
| A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose WeightNCT05996848 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 300 | 2023-08-15 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise AloneNCT05971940 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed●Now tracking | 559 | 2023-08-09 |
| A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the KneeNCT05931367 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed | 445 | 2023-08-01 |
| A Study of Once-Daily Oral Orforglipron (LY3502970) in Japanese Adult Participants With Obesity DiseaseNCT05931380 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed●Now tracking | 238 | 2023-07-31 |
| A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 DiabetesNCT05936151 · Eli Lilly and Company | Retatrutide | Phase 2 | Completed | 146 | 2023-07-20 |
| A Study of LY3437943 in Healthy Participants With a High Body Mass IndexNCT05959096 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 85 | 2023-07-18 |
| A Study of LY3437943 in Participants With Impaired and Normal Liver FunctionNCT05916560 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 43 | 2023-07-13 |
| A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment.NCT05936138 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 24 | 2023-07-13 |
| A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or OverweightNCT05929079 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed●Status change | 1152 | 2023-07-11 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or OverweightNCT05929066 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed | 2335 | 2023-07-10 |
| A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose WeightNCT05726227 · Novo Nordisk A/S | Semaglutide | Phase 3 | Active not recruiting●Now tracking | 212 | 2023-07-07 |
| Cathelicidin LL-37 Relation to Potentially Malignant LesionsNCT06219330 · Fayoum University | LL-37 | — | Completed | 45 | 2023-07-01 |
| Preoperative Weight Loss for Open Abdominal Wall ReconstructionNCT05925959 · Benjamin T. Miller | Liraglutide | — | Recruiting | 258 | 2023-06-19 |
| A Study of LY3502970 in Participants With Impaired and Normal Liver FunctionNCT05882032 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 29 | 2023-06-13 |
| A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 DiabetesNCT05872620 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed●Now tracking | 1613 | 2023-06-05 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related ComorbiditiesNCT05869903 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting●Results posted | 3127 | 2023-06-05 |
| A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular DiseaseNCT05882045 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed●Status change | 1946 | 2023-05-30 |
| Effects of GH and Lirglutide on AgRPNCT05681299 · Columbia University | Liraglutide | Phase 4 | Recruiting | 40 | 2023-05-01 |
| Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With DyslexiaNCT05832060 · Bambino Gesù Hospital and Research Institute | Selank | — | Unknown | 24 | 2023-05-01 |
| A Multiple Dose Study of LY3502970 in Healthy Overweight and Obese ParticipantsNCT05841238 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 52 | 2023-04-26 |
| Exenatide Pharmacokinetics and Pharmacodynamics in Gestational DiabetesNCT05482789 · Maisa N. Feghali, MD | Exenatide | Phase 4 | Recruiting | 13 | 2023-04-12 |
| Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2NCT05555589 · ReGenTree, LLC | Thymosin Beta-4 | Phase 3 | Recruiting | 70 | 2023-04-11 |
| A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose WeightNCT05813925 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 331 | 2023-04-03 |
| REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsNCT05669755 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 7101 | 2023-03-01 |
| Clinical Study of 18F-Exendin-4 in InsulinomaNCT07340437 · Sichuan Provincial People's Hospital | Exenatide | — | Completed | 20 | 2023-02-01 |
| A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose WeightNCT05394519 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 1200 | 2023-02-01 |
| A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in AmericaNCT05579249 · Novo Nordisk A/S | Liraglutide | Phase 4 | Completed | 500 | 2023-01-19 |
| Exenatide for Smoking Cessation and Prevention of Weight GainNCT05610800 · The University of Texas Health Science Center, Houston | Exenatide | Phase 2 | Completed | 140 | 2022-12-07 |
| A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)NCT05564039 · Eli Lilly and Company | Dulaglutide | Phase 4 | Completed | 282 | 2022-11-30 |
| A Study of LY3437943 in Healthy Participants and Participants With Impaired Renal FunctionNCT05611957 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 29 | 2022-11-16 |
| A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose WeightNCT05567796 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 3400 | 2022-11-01 |
| Semaglutide vs SitagliptinNCT05195944 · University Health Network, Toronto | Semaglutide | Phase 4 | Active not recruiting●Now tracking | 58 | 2022-10-26 |
| A Study of LY3437943 in Chinese Participants With Obesity Or OverweightNCT05548231 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 32 | 2022-10-24 |
| A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With ObesityNCT05556512 · Eli Lilly and Company | Tirzepatide | Phase 3 | Active not recruiting●Now tracking | 15374 | 2022-10-11 |
| LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 DiabetesNCT05313529 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Liraglutide | — | Completed●Status change | 396 | 2022-10-08 |
| PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 DiabetesNCT05390892 · Brigham and Women's Hospital | LiraglutideDulaglutide | Phase 4 | Recruiting | 6000 | 2022-09-26 |
| The Impact of Ibutamoren on Nonalcoholic Fatty Liver DiseaseNCT05364684 · Massachusetts General Hospital | MK-677 | Phase 2 | Completed | 12 | 2022-08-10 |
| A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy ParticipantsNCT05469126 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 26 | 2022-08-01 |
| Trifecta Research StudyNCT07717866 · Axial Therapeutic Research | Ipamorelin | — | Active not recruiting●Now tracking | 52 | 2022-08-01 |
| Efficacy and Safety Study of Thymosin Beta 4 in Patients With Acute Myocardial InfarctionNCT05984134 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 2 | Completed | 90 | 2022-07-15 |
| A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese ParticipantsNCT05445232 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 32 | 2022-07-08 |
| GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD)NCT05356104 · Chinese University of Hong Kong | Exenatide | Phase 2 | Recruiting | 110 | 2022-05-25 |
| A Study of Two Different Formulations of LY3502970 in Healthy ParticipantsNCT05341089 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 39 | 2022-05-17 |
| Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes MellitusNCT05662189 · Azienda Ospedaliero-Universitaria di Parma | Exenatide | — | Recruiting | 70 | 2022-03-15 |
| Adiponectin in Patients With Metabolic DisordersNCT07539584 · Moscow Regional Research and Clinical Institute (MONIKI) | Liraglutide | — | Completed | 130 | 2022-03-01 |
| Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 DiabetesNCT04307797 · Cambridge University Hospitals NHS Foundation Trust | Exenatide | Phase 4 | Completed | 10 | 2022-01-18 |
| A Study of LY3502970 in Japanese Participants With Type 2 Diabetes MellitusNCT05086445 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed●Now tracking | 62 | 2021-11-12 |
| A Multiple Dose Study of LY3502970 in Healthy ParticipantsNCT05051566 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 26 | 2021-09-16 |
| Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)NCT04897802 · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Exenatide | Phase 4 | Completed | 42 | 2021-09-13 |
| Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes StudyNCT05220917 · Brigham and Women's Hospital | LiraglutideDulaglutideExenatide | — | Active not recruiting | 781430 | 2021-08-01 |
| GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose IntoleranceNCT04731272 · University of Pennsylvania | Dulaglutide | Phase 2 | Recruiting | 30 | 2021-07-16 |
| Comparison of Type 2 Diabetes Pharmacotherapy RegimensNCT05073692 · Kaiser Permanente | Exenatide | — | Completed | 241981 | 2021-07-01 |
| A Study of LY3437943 in Japanese Participants With Type 2 Diabetes Mellitus (T2DM)NCT04823208 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 64 | 2021-05-24 |
| A Study of LY3437943 in Participants Who Have Obesity or Are OverweightNCT04881760 · Eli Lilly and Company | Retatrutide | Phase 2 | Completed | 338 | 2021-05-20 |
| A Study of LY3437943 in Participants With Type 2 DiabetesNCT04867785 · Eli Lilly and Company | Retatrutide | Phase 2 | Completed | 281 | 2021-05-13 |
| Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)NCT04822181 · Novo Nordisk A/S | Semaglutide | Phase 3 | Active not recruiting●Now tracking | 1205 | 2021-04-01 |
| Peri-implant Vitamin D and Cathelicidin (LL-37) LevelsNCT06867250 · Altinbas University | LL-37 | — | Completed | 33 | 2021-04-01 |
| SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With ObesityNCT04775082 · Novo Nordisk A/S | Liraglutide | Phase 3 | Active not recruiting | 78 | 2021-03-04 |
| Cathelicidin LL-37 Levels in the GCF and the Saliva of Smokers and Non-smokers With Stage III,IV PeriodontitisNCT04861493 · Cairo University | LL-37 | — | Completed | 60 | 2021-02-23 |
| Brain Activation and Satiety in Children 2NCT04520490 · Seattle Children's Hospital | Exenatide | Phase 3 | Active not recruiting | 63 | 2021-01-28 |
| Safety and Efficacy Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction.InfarctionNCT05485818 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 2 | Completed | 62 | 2020-11-23 |
| Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic SyndromeNCT04575844 · University of Virginia | Liraglutide | Phase 4 | Recruiting | 80 | 2020-11-01 |
| Exenatide Once-weekly as a Treatment for Multiple System AtrophyNCT04431713 · University College, London | Exenatide | Phase 2 | Completed | 50 | 2020-09-16 |
| A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesNCT04255433 · Eli Lilly and Company | Dulaglutide | Phase 3 | Completed | 13299 | 2020-05-29 |
| A Clinical Study of NLY01 in Patient's With Early Parkinson's DiseaseNCT04154072 · Neuraly, Inc. | Exenatide | Phase 2 | Completed | 255 | 2020-02-27 |
| Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's DiseaseNCT04232969 · University College, London | Exenatide | Phase 3 | Completed | 194 | 2020-01-20 |
| A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM)NCT04143802 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 72 | 2019-12-18 |
| A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial InfarctionNCT01311518 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Withdrawn | 0 | 2019-07 |
| A Study of LY3502970 in Healthy ParticipantsNCT03929744 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 133 | 2019-06-12 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3NCT03937882 · ReGenTree, LLC | Thymosin Beta-4 | Phase 3 | Completed●Results posted | 700 | 2019-05-24 |
| A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 DiabetesNCT03811561 · Novo Nordisk A/S | Semaglutide | Phase 3 | Active not recruiting●Now tracking | 1500 | 2019-05-08 |
| Liraglutide Effect in Atrial FibrillationNCT03856632 · University of Miami | Liraglutide | Phase 4 | Active not recruiting | 60 | 2019-03-18 |
| A Safety Study of LY3437943 Given as a Single Injection in Healthy ParticipantsNCT03841630 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 45 | 2019-03-13 |
| Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)NCT03883412 · University of Virginia | Liraglutide | Phase 4 | Recruiting●Now tracking | 60 | 2019-02-28 |
| Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related DiseaseNCT06725693 · Tianjin Medical University | Exenatide | — | Recruiting | 500 | 2019-02-01 |
| Growth Hormone Dynamics and Cardiac Steatosis in HIVNCT03826160 · Massachusetts General Hospital | Tesamorelin | — | Completed | 23 | 2019-01-30 |
| Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular RiskNCT03375788 · Massachusetts General Hospital | SermorelinTesamorelin | Phase 2 | Completed | 51 | 2019-01-17 |
| A Phase 1b Study of Thymosin Beta 4 in Healthy VolunteersNCT04555850 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 1 | Completed | 30 | 2018-07-30 |
| Tesamorelin to Improve Functional Outcomes After Peripheral Nerve InjuryNCT03150511 · Johns Hopkins University | Tesamorelin | Phase 2 | Recruiting | 36 | 2018-06-01 |
| Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance ImagingNCT03498001 · Centre Hospitalier Universitaire Dijon | LiraglutideDulaglutide | — | Completed | 42 | 2018-04-16 |
| A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular DiseaseNCT03492580 · Janssen Research & Development, LLC | DulaglutideExenatide | — | Completed | 714582 | 2018-02-22 |
| Body Composition and Adipose Tissue in HIVNCT03226821 · Columbia University | Tesamorelin | Phase 4 | Terminated | 6 | 2018-02-07 |
| The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their CombinationNCT03878706 · University of Athens | LiraglutideMOTS-c | — | Recruiting | 240 | 2017-11-03 |
| The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive ImpairmentNCT02553603 · The University of Texas Medical Branch, Galveston | SermorelinTesamorelin | Phase 1 | Completed | 22 | 2017-07-18 |
| A Phase 1a Study of Thymosin Beta 4 in Healthy VolunteersNCT04555824 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 1 | Completed | 54 | 2017-07-17 |
| Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected PersonsNCT02572323 · University of California, San Diego | Tesamorelin | Phase 2 | Completed | 73 | 2017-02-15 |
| Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma TherapyNCT02860923 · University Hospital, Bordeaux | Exenatide | Phase 3 | Completed | 42 | 2017-01-11 |
| Study of Intranasal Octreotide (DP1038) in Healthy Adult VolunteersNCT03031535 · Dauntless Pharmaceuticals | Sermorelin | Phase 1 | Completed | 32 | 2017-01 |
| Saxenda: Underlying Mechanisms and Clinical OutcomesNCT02944500 · Beth Israel Deaconess Medical Center | Liraglutide | Phase 4 | Active not recruiting | 28 | 2016-11 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2NCT02974907 · ReGenTree, LLC | Thymosin Beta-4 | Phase 3 | Completed | 601 | 2016-11 |
| Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current InsomniaNCT02931474 · National Institute of Nursing Research (NINR) | Tesamorelin | Phase 2 | Withdrawn | 0 | 2016-10-06 |
| Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.NCT02806414 · University of California, San Diego | LL-37 | Phase 1/Phase 2 | Completed | 25 | 2016-07 |
| Pharmacogenomics of GLP1 Receptor AgonistsNCT05762744 · University of Maryland, Baltimore | Exenatide | Phase 1 | Terminated | 63 | 2016-06-01 |
| Dehydroepiandrosterone Versus Growth Hormone in Women Undergoing ICSI With Expected Poor Ovarian ResponseNCT02736591 · Cairo University | Sermorelin | Phase 3 | Unknown | 210 | 2016-06 |
| Timely Detection of Treatment Emergent Serious and Non-serious Adverse Events for Saxenda® in Mexican PatientsNCT02773355 · Novo Nordisk A/S | Liraglutide | — | Completed | 27 | 2016-05-16 |
| GLP-1 and Hyperoxia for Organ Protection in Heart SurgeryNCT02673931 · Copenhagen University Hospital, Rigshospitalet | Exenatide | — | Unknown●Status change | 1400 | 2016-02 |
| Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Major Surgical Procedures.NCT02138591 · University of Missouri, Kansas City | LL-37 | Phase 3 | Withdrawn | 0 | 2016-02 |
| Cohort Of DEafness-gene ScreeningNCT06133946 · Affiliated Hospital of Nantong University | MOTS-c | — | Active not recruiting | 35920 | 2016-01-01 |
| Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal SyndromeNCT02251431 · Baylor Research Institute | Exenatide | Phase 3 | Completed | 57 | 2015-11 |
| PCO-02 - Safety and Pharmacokinetics TrialNCT02637284 · PharmaCotherapia d.o.o. | BPC-157 | Phase 1 | Unknown | 42 | 2015-10 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1NCT02597803 · ReGenTree, LLC | Thymosin Beta-4 | Phase 2/Phase 3 | Completed | 317 | 2015-09 |
| Tesamorelin Effects on Liver Fat and Histology in HIVNCT02196831 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 61 | 2015-07-01 |
| Estradiol-Receptor Blockade in Older Men and WomenNCT02271282 · Mayo Clinic | Sermorelin | Phase 1 | Completed | 40 | 2014-12 |
| Liver and Fat Regulation in Overweight Adolescent GirlsNCT02157974 · University of Colorado, Denver | Exenatide | Phase 2/Phase 3 | Completed | 92 | 2014-08 |
| Effect of Victoza on Dietary Preferences and Habit in Patients With Type 2 DiabetesNCT02674893 · Centre Hospitalier Universitaire Dijon | Liraglutide | Phase 4 | Terminated | 48 | 2014-02-04 |
| Platelet Reactivity, B-amyloid, MOTS-c and Mortality of Type II Diabetics With CADNCT04027712 · University of Athens | MOTS-c | — | Unknown | 120 | 2014-01-01 |
| Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD)NCT02507245 · Stefania La Grutta, MD | Sermorelin | — | Completed | 48 | 2014-01 |
| Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone AnalogueNCT01632592 · Massachusetts General Hospital | SermorelinTesamorelin | — | Withdrawn | 0 | 2014-01 |
| GLP-1's Effect on Cardiac Parameters and Mesenteric Blood FlowNCT01988545 · Zealand University Hospital | Exenatide | — | Completed●Now tracking | 8 | 2013-11-01 |
| A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 DiabetesNCT01794143 · GRADE Study Group | Liraglutide | Phase 3 | Completed | 7850 | 2013-05 |
| Long-term Observational Study in HIV Subjects Exposed to EGRIFTA®NCT01579695 · Theratechnologies | Tesamorelin | — | Terminated | 391 | 2013-02 |
| Effects of Transcranial Magnetic Stimulation on Object RecognitionNCT01747200 · National Institute of Neurological Disorders and Stroke (NINDS) | Selank | — | Completed | 13 | 2012-11-16 |
| Effect of Liraglutide on Fatty Liver Content and Lipoprotein MetabolismNCT02721888 · Centre Hospitalier Universitaire Dijon | Liraglutide | Phase 4 | Terminated | 127 | 2012-07-10 |
| Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®NCT01591902 · Theratechnologies | Tesamorelin | Phase 4 | Terminated | 129 | 2012-06 |
| Egrifta Replacement and Sleep Disordered BreathingNCT01788462 · Johns Hopkins University | Tesamorelin | — | Withdrawn | 0 | 2012-05 |
| Effects of Smoking and Vitamin D3 on the Levels of Human Cathelicidin Peptide LL-37NCT03923218 · Gazi University | LL-37 | — | Completed | 60 | 2011-12 |
| Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle WastingNCT01388920 · Theratechnologies | Tesamorelin | Phase 2 | Terminated | 3 | 2011-09 |
| Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry EyeNCT01387347 · ReGenTree, LLC | Thymosin Beta-4 | Phase 2 | Completed | 72 | 2011-08 |
| Effects of Aminocaproic Acid (ACA) on Rosacea-specific InflammationNCT01398280 · University of California, San Diego | LL-37 | EARLY_Phase 1 | Completed | 15 | 2011-07 |
| Vitamin D in Ventilated ICU PatientsNCT01372995 · Emory University | LL-37 | Phase 2 | Completed | 31 | 2011-07 |
| Three Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the ElderlyNCT01410799 · University of Pennsylvania | Sermorelin | Phase 2 | Terminated | 13 | 2011-05 |
| Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal FunctionNCT01280344 · Helsinn Therapeutics (U.S.), Inc | Ipamorelin | Phase 2 | Completed | 320 | 2011-04 |
| Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry EyeNCT01393132 · Michigan Cornea Consultants, PC | Thymosin Beta-4 | Phase 2 | Completed | 9 | 2011-03 |
| VRS-317 in Adult Subjects With Growth Hormone DeficiencyNCT01359488 · Versartis Inc. | Sermorelin | Phase 1 | Completed | 50 | 2011-03 |
| Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese DiabeticsNCT02042664 · Assistance Publique Hopitaux De Marseille | Exenatide | Phase 3 | Completed | 44 | 2011-01 |
| Effects of Growth Hormone Releasing Hormone in HIVNCT01263717 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 54 | 2010-12 |
| Growth Hormone Secretagogue MK-0677's Effect on Lean Body Mass in Chronic Kidney Disease Stage 4/5 SubjectsNCT01343641 · University of Virginia | MK-677 | Phase 2 | Withdrawn | 0 | 2009-03 |
| Effects of Short-term Growth Hormone in HIV-infected PatientsNCT00795210 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 25 | 2009-02 |
| Effect of Short Term Growth Hormone Releasing Hormone in Healthy MenNCT00850564 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 15 | 2009-02 |
| Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DMNCT01107717 · The University of Texas Health Science Center at San Antonio | Exenatide | Phase 4 | Completed | 318 | 2009-01 |
| Vitamin D in Active Tuberculosis (TB) StudyNCT00788320 · Atlanta VA Medical Center | LL-37 | — | Withdrawn | 0 | 2008-10 |
| Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are ObeseNCT00675506 · Massachusetts General Hospital | SermorelinTesamorelin | Phase 2 | Completed | 60 | 2008-07 |
| Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive PatientsNCT02012556 · Theratechnologies | SermorelinTesamorelin | Phase 1 | Completed | 18 | 2008-05 |
| A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy VolunteersNCT00743769 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 1 | Withdrawn | 0 | 2008-04 |
| Safety and Efficacy of Ipamorelin for Management of Post-Operative IleusNCT00672074 · Helsinn Therapeutics (U.S.), Inc | Ipamorelin | Phase 2 | Completed | 117 | 2008-04 |
| Six Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the ElderlyNCT00807365 · Johns Hopkins University | Sermorelin | Phase 2 | Terminated | 5 | 2007-12-17 |
| A Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 for Treating Corneal WoundsNCT00598871 · ReGenTree, LLC | Thymosin Beta-4 | Phase 2 | Terminated | 12 | 2007-12 |
| Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) ProtocolNCT00679042 · CellTrans Inc. | Exenatide | Phase 3 | Active not recruiting | 21 | 2007-09-05 |
| TH9507 Extension Study in Patients With HIV-Associated LipodystrophyNCT00608023 · Theratechnologies | SermorelinTesamorelin | Phase 3 | Completed | 263 | 2007-08 |
| Sexually Dimorphic Effects of GHRH in Adult Growth Hormone TestingNCT00324064 · Children's Mercy Hospital Kansas City | Sermorelin | — | Completed | 90 | 2007-07 |
| Adult Growth Hormone Deficiency and Cardiovascular RiskNCT00720902 · Columbia University | Sermorelin | Phase 4 | Terminated | 7 | 2007-02 |
| GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial EmulationNCT07677865 · West China Hospital | Liraglutide | — | Completed | 213891 | 2007-01-01 |
| Growth Hormone Secretagogue MK-0677 Effect on IGF-1 Levels in ESRD PatientsNCT00395291 · University of Virginia | MK-677 | — | Completed | 49 | 2006-08 |
| Study of Thymosin Beta 4 in Patients With Venous Stasis UlcersNCT00832091 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Completed | 72 | 2006-07 |
| Study of Thymosin Beta 4 in Patients With Pressure UlcersNCT00382174 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Completed | 72 | 2006-05 |
| A Phase 2 Study on Effect of Thymosin Beta 4 on Wound Healing in Patients With Epidermolysis BullosaNCT00311766 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Terminated | 30 | 2006-02 |
| SMART: Somatotrophics, Memory, and Aging Research TrialNCT00257712 · University of Washington | SermorelinTesamorelin | Phase 2 | Completed | 151 | 2006-02 |
| A Study to Evaluate CJC 1295 in HIV Patients With Visceral ObesityNCT00267527 · ConjuChem | CJC-1295 | Phase 2 | Terminated | 120 | 2005-12 |
| Treatment of Sarcopenia in Post-Hip Fracture Patients (0677-032)NCT00128115 · Merck Sharp & Dohme LLC | MK-677 | Phase 2 | Terminated | 83 | 2005-09 |
| Efficacy and Safety of an Oral Growth Hormone Drug in the Treatment of FibromyalgiaNCT00116129 · Bennett, Robert, M.D. | MK-677 | Phase 2 | Completed | 64 | 2005-07 |
| TH9507 in Patients With HIV-Associated LipodystrophyNCT00123253 · Theratechnologies | SermorelinTesamorelin | Phase 3 | Completed | 412 | 2005-06 |
| The Effect of GHRH Therapy on Myocardial Structure and Function in Congestive Heart FailureNCT00791843 · University of Pennsylvania | Sermorelin | Phase 2 | Completed | 3 | 2004-03 |
| Comparative Validation of the Growth Hormone Releasing Hormone and Arginine Test for the Diagnosis of Adult Growth Hormone DeficiencyNCT01060488 · Merck KGaA, Darmstadt, Germany | Sermorelin | Phase 3 | Completed | 69 | 2004-01 |
| Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)NCT00074529 · Merck Sharp & Dohme LLC | MK-677 | Phase 2 | Completed | 512 | 2003-10 |
| Safety Study of TH9507 in Subjects With Stable, Type 2 DiabetesNCT01264497 · Theratechnologies | Tesamorelin | Phase 2 | Completed | 55 | 2002-02 |
| Diagnosing Adult Growth Hormone DeficiencyNCT03018886 · Helsinki University Central Hospital | Sermorelin | — | Completed | 160 | 2001-05 |
| Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older AdultsNCT00474279 · University of Virginia | MK-677 | Phase 1/Phase 2 | Completed | 72 | 1998-07 |
| Growth Hormone Releasing Hormone (GHRH) Treatment for Age-Related Sleep DisturbancesNCT00000380 · University of Washington | Sermorelin | — | Completed | — | 1996-06 |
| Study of the Effect of Growth Hormone-Releasing Hormone Antagonist on Growth Hormone Release in AcromegalyNCT00004332 · National Center for Research Resources (NCRR) | Sermorelin | — | Completed | 148 | 1993-05 |
| Pre-approval Expanded Access of Retatrutide (LY3437943)NCT07629401 · Eli Lilly and Company | Retatrutide | — | Available | — | — |