Longevity
Biomarkers, healthy aging, preventative health, and lifespan research.
88 articles in Longevity · page 3 of 8
Fiber and Lifespan: The Underrated Longevity Lever
Dietary fiber shows one of the most consistent mortality associations in nutrition science — and most people still fall well short of the intake.
Read →Glucosamine and Mortality: The Surprising Signal
UK Biobank and other cohorts link regular glucosamine use to lower death rates. Why that is genuinely interesting, and why it is not proof.
Read →Is NMN Worth Taking?
NMN reliably raises a NAD+ biomarker in blood. Whether that translates into a longer or healthier life in humans is still an open question.
Read →Rapamycin vs Metformin: The Two Longevity Drugs Compared
Two prescription drugs repurposed by longevity enthusiasts on animal data and one unproven trial. Neither has been shown to extend human life.
Read →The Blueprint Protocol: A Skeptical Look
Bryan Johnson's Blueprint is the most measured self-experiment in longevity. That is not the same as proof. What is evidence-based, and what isn't.
Read →Bone Density and Healthy Aging
Why skeletal health quietly determines independence in later decades, and what the trials say actually helps — loading and nutrition.
Read →DHEA, Hormones, and Aging
A popular anti-aging hormone weighed against pooled trial data showing small, sex-specific effects. What DHEA does and doesn't do.
Read →Cognitive Reserve and Brain Aging
Cognitive reserve is the buffer that protects thinking with age. What the evidence says builds it, and why it is not the same as brain size.
Read →Sarcopenia: Fighting Age-Related Muscle Loss
Sarcopenia has agreed diagnostic cut-points, one intervention with Cochrane-grade evidence — progressive resistance training — and no approved drug.
Read →Reading a Longevity Study: Mice Aren't Men
What the NIA Interventions Testing Program and the animal-to-human translation data show about how much a mouse lifespan result is actually worth.
Read →Frailty and Aging: Prevention Strategies
Frailty is partly preventable and sometimes reversible. What the trial evidence supports on exercise, protein, and multi-domain programs.
Read →Why Most Longevity Supplements Disappoint
The structural reasons the supplement aisle rarely matches the press releases: preclinical models, dose gaps, and endpoints that never move.
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